G4G (p.Gly4Gly) variant of LRRK2 (Q5S007)
G4G (p.Gly4Gly) in LRRK2 (Q5S007) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data, published literature, and structural context.
G4G (p.Gly4Gly) variant details
- p.Gly4Gly
- gnomAD 12-40225143-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.28
- CADD 14.00
- Most common in the Non-Finnish European population (allele frequency 9.9e-07)
- Structural context available
- Literature evidence available