C9G (p.Cys9Gly) variant of LRRK2 (Q5S007)
C9G (p.Cys9Gly) in LRRK2 (Q5S007) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data and structural context.
C9G (p.Cys9Gly) variant details
- p.Cys9Gly
- cosmic curated COSV54159
- ExAC rs200688492
- gnomAD rs200688492
- Missense
- Variant Prioritization Score for Impact Estimate 0.132
- REVEL 0.05
- MetaLR 0.07
- MetaSVM -1.00
- CADD 19.00
- PolyPhen-2 0.01
- SIFT 0.09
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available