C9C (p.Cys9Cys) variant of LRRK2 (Q5S007)
C9C (p.Cys9Cys) in LRRK2 (Q5S007) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data, published literature, and structural context.
C9C (p.Cys9Cys) variant details
- p.Cys9Cys
- rs1592124460
- gnomAD 12-40225158-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.377
- CADD 14.50
- Most common in the Ashkenazi Jewish population (allele frequency 5.1e-05)
- Structural context available
- Literature evidence available