V8M (p.Val8Met) variant of LPL (Lipoprotein lipase)
V8M (p.Val8Met) in LPL (Lipoprotein lipase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data and structural context.
V8M (p.Val8Met) variant details
- p.Val8Met
- TOPMed rs920363064
- Missense
- Variant Prioritization Score for Impact Estimate 0.503
- MetaLR 0.37
- MetaSVM -0.59
- CADD 22.40
- PolyPhen-2 0.02
- SIFT 0.06
- Most common in the Non-Finnish European population (allele frequency 5.4e-06)
- Structural context available