V8L (p.Val8Leu) variant of LPL (Lipoprotein lipase)
V8L (p.Val8Leu) in LPL (Lipoprotein lipase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data, published literature, and structural context.
V8L (p.Val8Leu) variant details
- p.Val8Leu
- gnomAD 8-19939462-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.44
- MetaLR 0.18
- MetaSVM -0.80
- CADD 14.30
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 3.6e-06)
- Structural context available
- Literature evidence available