V25L (p.Val25Leu) variant of LPL (Lipoprotein lipase)
V25L (p.Val25Leu) in LPL (Lipoprotein lipase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
V25L (p.Val25Leu) variant details
- p.Val25Leu
- gnomAD rs1395752390
- Missense
- Variant Prioritization Score for Impact Estimate 0.355
- MetaLR 0.40
- MetaSVM -0.58
- CADD 16.50
- PolyPhen-2 0.00
- SIFT 0.89
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available