R22H (p.Arg22His) variant of LPL (Lipoprotein lipase)
R22H (p.Arg22His) in LPL (Lipoprotein lipase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data, published literature, and structural context.
R22H (p.Arg22His) variant details
- p.Arg22His
- gnomAD 8-19939505-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.31
- MetaLR 0.53
- MetaSVM -0.65
- CADD 13.40
- PolyPhen-2 0.00
- SIFT 0.61
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available