L6R (p.Leu6Arg) variant of LPL (Lipoprotein lipase)
L6R (p.Leu6Arg) in LPL (Lipoprotein lipase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data and structural context.
L6R (p.Leu6Arg) variant details
- p.Leu6Arg
- Ensembl rs2069809872
- Missense
- Variant Prioritization Score for Impact Estimate 0.495
- MetaLR 0.66
- MetaSVM 0.13
- CADD 24.90
- PolyPhen-2 0.59
- SIFT 0.01
- Most common in the South Asian population (allele frequency 0.00021)
- Structural context available