L6P (p.Leu6Pro) variant of LPL (Lipoprotein lipase)
L6P (p.Leu6Pro) in LPL (Lipoprotein lipase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data, published literature, and structural context.
L6P (p.Leu6Pro) variant details
- p.Leu6Pro
- gnomAD 8-19939457-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.508
- MetaLR 0.68
- MetaSVM 0.17
- CADD 25.20
- PolyPhen-2 0.67
- SIFT 0.13
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available