L18D (p.Leu18Asp) variant of LPL (Lipoprotein lipase)
L18D (p.Leu18Asp) in LPL (Lipoprotein lipase) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.78 / 1. The record also includes population frequency data, published literature, and structural context.
L18D (p.Leu18Asp) variant details
- p.Leu18Asp
- gnomAD 8-19939486-CAG-C
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.781
- CADD 27.80
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- Literature evidence available