I37M (p.Ile37Met) variant of LPL (Lipoprotein lipase)
I37M (p.Ile37Met) in LPL (Lipoprotein lipase) is a missense change. Clinical records from EBI and UniProt describe it as likely benign. The available variant effect predictions contribute to a CATVariant prioritization score of 0.06 / 1. The record also includes population frequency data and structural context.
I37M (p.Ile37Met) variant details
- p.Ile37Met
- ESP rs374067507
- ExAC rs374067507
- TOPMed rs374067507
- gnomAD rs374067507
- Likely benign
- Missense
- Variant Prioritization Score for Impact Estimate 0.0619
- CADD 0.27
- PolyPhen-2 1.00
- SIFT 0.01
- EBI: Likely benign
- UniProt: Likely benign
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available