I35Y (p.Ile35Tyr) variant of LPL (Lipoprotein lipase)
I35Y (p.Ile35Tyr) in LPL (Lipoprotein lipase) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data, published literature, and structural context.
I35Y (p.Ile35Tyr) variant details
- p.Ile35Tyr
- gnomAD 8-19948189-A-AT
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.475
- CADD 25.40
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available