E51D (p.Glu51Asp) variant of LPL (Lipoprotein lipase)
E51D (p.Glu51Asp) in LPL (Lipoprotein lipase) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
E51D (p.Glu51Asp) variant details
- p.Glu51Asp
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.19
- CADD 8.57
- PolyPhen-2 0.01
- SIFT 0.94
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available