D36Y (p.Asp36Tyr) variant of LPL (Lipoprotein lipase)
D36Y (p.Asp36Tyr) in LPL (Lipoprotein lipase) is a missense change. Clinical records from EBI and UniProt describe it as benign. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data and structural context.
D36Y (p.Asp36Tyr) variant details
- p.Asp36Tyr
- 1000Genomes rs1801177
- ESP rs1801177
- ExAC rs1801177
- TOPMed rs1801177
- Benign
- Missense
- Variant Prioritization Score for Impact Estimate 0.5
- CADD 24.20
- PolyPhen-2 0.97
- SIFT 0.02
- EBI: Benign
- UniProt: Benign
- Most common in the African/African-American population (allele frequency 6e-05)
- Structural context available