A5T (p.Ala5Thr) variant of LPL (Lipoprotein lipase)
A5T (p.Ala5Thr) in LPL (Lipoprotein lipase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
A5T (p.Ala5Thr) variant details
- p.Ala5Thr
- gnomAD rs1208045265
- Missense
- Variant Prioritization Score for Impact Estimate 0.382
- MetaLR 0.50
- MetaSVM -0.36
- CADD 21.40
- PolyPhen-2 0.00
- SIFT 0.59
- Most common in the Latino/Admixed American population (allele frequency 2.3e-05)
- Structural context available