A5D (p.Ala5Asp) variant of LPL (Lipoprotein lipase)
A5D (p.Ala5Asp) in LPL (Lipoprotein lipase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data, published literature, and structural context.
A5D (p.Ala5Asp) variant details
- p.Ala5Asp
- gnomAD 8-19939454-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.403
- MetaLR 0.59
- MetaSVM -0.10
- CADD 18.30
- PolyPhen-2 0.25
- SIFT 0.13
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available