A20T (p.Ala20Thr) variant of LPL (Lipoprotein lipase)
A20T (p.Ala20Thr) in LPL (Lipoprotein lipase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
A20T (p.Ala20Thr) variant details
- p.Ala20Thr
- ExAC rs774768909
- gnomAD rs774768909
- Missense
- Variant Prioritization Score for Impact Estimate 0.392
- MetaLR 0.57
- MetaSVM -0.76
- CADD 16.80
- PolyPhen-2 0.01
- SIFT 0.47
- Most common in the Latino/Admixed American population (allele frequency 4.5e-05)
- Structural context available