W52C (p.Trp52Cys) variant of LPA (Apolipoprotein(a))
W52C (p.Trp52Cys) in LPA (Apolipoprotein(a)) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.63 / 1. The record also includes population frequency data and structural context.
W52C (p.Trp52Cys) variant details
- p.Trp52Cys
- TOPMed rs1779981806
- Missense
- Variant Prioritization Score for Impact Estimate 0.632
- REVEL 0.51
- MetaLR 0.92
- MetaSVM 0.51
- CADD 23.10
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Finnish in Finland (FIN) population (allele frequency 1.9e-05)
- Structural context available