W211C (p.Trp211Cys) variant of LPA (Apolipoprotein(a))
W211C (p.Trp211Cys) in LPA (Apolipoprotein(a)) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data and structural context.
W211C (p.Trp211Cys) variant details
- p.Trp211Cys
- Ensembl rs1779835564
- Missense
- Variant Prioritization Score for Impact Estimate 0.519
- REVEL 0.39
- MetaLR 0.49
- MetaSVM -0.06
- CADD 27.10
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9.3e-05)
- Structural context available