V7L (p.Val7Leu) variant of LPA (Apolipoprotein(a))
V7L (p.Val7Leu) in LPA (Apolipoprotein(a)) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data and structural context.
V7L (p.Val7Leu) variant details
- p.Val7Leu
- gnomAD rs1353619698
- Missense
- Variant Prioritization Score for Impact Estimate 0.108
- REVEL 0.08
- MetaLR 0.19
- MetaSVM -0.89
- CADD 0.36
- PolyPhen-2 0.02
- SIFT 0.44
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available