V6A (p.Val6Ala) variant of LPA (Apolipoprotein(a))
V6A (p.Val6Ala) in LPA (Apolipoprotein(a)) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
V6A (p.Val6Ala) variant details
- p.Val6Ala
- gnomAD rs1235491413
- Missense
- Variant Prioritization Score for Impact Estimate 0.311
- REVEL 0.16
- MetaLR 0.41
- MetaSVM -0.48
- CADD 20.20
- PolyPhen-2 0.45
- SIFT 0.60
- Most common in the REMAINING population (allele frequency 3.3e-05)
- Structural context available