V24A (p.Val24Ala) variant of LPA (Apolipoprotein(a))
V24A (p.Val24Ala) in LPA (Apolipoprotein(a)) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
V24A (p.Val24Ala) variant details
- p.Val24Ala
- 1000Genomes rs199786104
- ExAC rs199786104
- TOPMed rs199786104
- Missense
- Variant Prioritization Score for Impact Estimate 0.155
- REVEL 0.04
- MetaLR 0.07
- MetaSVM -1.04
- CADD 11.20
- PolyPhen-2 0.10
- SIFT 0.16
- Most common in the 1KG:CHB population (allele frequency 0.0049)
- Structural context available