V197M (p.Val197Met) variant of LPA (Apolipoprotein(a))
V197M (p.Val197Met) in LPA (Apolipoprotein(a)) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
V197M (p.Val197Met) variant details
- p.Val197Met
- gnomAD rs1233089347
- Missense
- Variant Prioritization Score for Impact Estimate 0.358
- REVEL 0.14
- MetaLR 0.13
- MetaSVM -1.01
- CADD 23.20
- PolyPhen-2 1.00
- SIFT 0.02
- Most common in the Latino/Admixed American population (allele frequency 5.9e-05)
- Structural context available