T64I (p.Thr64Ile) variant of LPA (Apolipoprotein(a))
T64I (p.Thr64Ile) in LPA (Apolipoprotein(a)) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
T64I (p.Thr64Ile) variant details
- p.Thr64Ile
- TOPMed rs1779980645
- gnomAD rs1779980645
- Missense
- Variant Prioritization Score for Impact Estimate 0.362
- REVEL 0.16
- MetaLR 0.22
- MetaSVM -0.86
- CADD 18.40
- PolyPhen-2 0.79
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available