T56I (p.Thr56Ile) variant of LPA (Apolipoprotein(a))
T56I (p.Thr56Ile) in LPA (Apolipoprotein(a)) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
T56I (p.Thr56Ile) variant details
- p.Thr56Ile
- TOPMed rs1299567827
- gnomAD rs1299567827
- Missense
- Variant Prioritization Score for Impact Estimate 0.119
- REVEL 0.11
- MetaLR 0.05
- MetaSVM -1.05
- CADD 2.17
- PolyPhen-2 0.92
- SIFT 0.39
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available