T39R (p.Thr39Arg) variant of LPA (Apolipoprotein(a))
T39R (p.Thr39Arg) in LPA (Apolipoprotein(a)) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
T39R (p.Thr39Arg) variant details
- p.Thr39Arg
- ESP rs376418933
- ExAC rs376418933
- TOPMed rs376418933
- gnomAD rs376418933
- Missense
- Variant Prioritization Score for Impact Estimate 0.354
- REVEL 0.33
- MetaLR 0.24
- MetaSVM -0.85
- CADD 21.00
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the Ashkenazi Jewish population (allele frequency 0.00019)
- Structural context available