T39M (p.Thr39Met) variant of LPA (Apolipoprotein(a))
T39M (p.Thr39Met) in LPA (Apolipoprotein(a)) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
T39M (p.Thr39Met) variant details
- p.Thr39Met
- ESP rs376418933
- ExAC rs376418933
- TOPMed rs376418933
- gnomAD rs376418933
- Missense
- Variant Prioritization Score for Impact Estimate 0.328
- REVEL 0.26
- MetaLR 0.32
- MetaSVM -0.78
- CADD 21.10
- PolyPhen-2 0.99
- SIFT 0.04
- Most common in the Finnish in Finland (FIN) population (allele frequency 0.0034)
- Structural context available