T217M (p.Thr217Met) variant of LPA (Apolipoprotein(a))
T217M (p.Thr217Met) in LPA (Apolipoprotein(a)) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
T217M (p.Thr217Met) variant details
- p.Thr217Met
- TOPMed rs1779835311
- Missense
- Variant Prioritization Score for Impact Estimate 0.171
- REVEL 0.13
- MetaLR 0.16
- MetaSVM -0.92
- CADD 14.20
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 9.2e-05)
- Structural context available