T204M (p.Thr204Met) variant of LPA (Apolipoprotein(a))
T204M (p.Thr204Met) in LPA (Apolipoprotein(a)) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data and structural context.
T204M (p.Thr204Met) variant details
- p.Thr204Met
- gnomAD rs1327153515
- Missense
- Variant Prioritization Score for Impact Estimate 0.479
- REVEL 0.31
- MetaLR 0.59
- MetaSVM -0.33
- CADD 25.40
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the South Asian population (allele frequency 0.00019)
- Structural context available