S35N (p.Ser35Asn) variant of LPA (Apolipoprotein(a))
S35N (p.Ser35Asn) in LPA (Apolipoprotein(a)) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data and structural context.
S35N (p.Ser35Asn) variant details
- p.Ser35Asn
- TOPMed rs565044567
- gnomAD rs565044567
- Missense
- Variant Prioritization Score for Impact Estimate 0.107
- REVEL 0.04
- MetaLR 0.08
- MetaSVM -0.91
- CADD 0.34
- PolyPhen-2 0.32
- SIFT 0.24
- Most common in the Non-Finnish European population (allele frequency 5.9e-05)
- Structural context available