R62W (p.Arg62Trp) variant of LPA (Apolipoprotein(a))
R62W (p.Arg62Trp) in LPA (Apolipoprotein(a)) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
R62W (p.Arg62Trp) variant details
- p.Arg62Trp
- ExAC rs771863444
- TOPMed rs771863444
- gnomAD rs771863444
- Missense
- Variant Prioritization Score for Impact Estimate 0.265
- REVEL 0.21
- MetaLR 0.19
- MetaSVM -0.95
- CADD 22.00
- PolyPhen-2 1.00
- SIFT 0.18
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available