R62S (p.Arg62Ser) variant of LPA (Apolipoprotein(a))
R62S (p.Arg62Ser) in LPA (Apolipoprotein(a)) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
R62S (p.Arg62Ser) variant details
- p.Arg62Ser
- TOPMed rs1779980745
- Missense
- Variant Prioritization Score for Impact Estimate 0.244
- REVEL 0.09
- MetaLR 0.08
- MetaSVM -1.03
- CADD 18.60
- PolyPhen-2 0.99
- SIFT 0.40
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available