R62G (p.Arg62Gly) variant of LPA (Apolipoprotein(a))
R62G (p.Arg62Gly) in LPA (Apolipoprotein(a)) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
R62G (p.Arg62Gly) variant details
- p.Arg62Gly
- ExAC rs771863444
- TOPMed rs771863444
- gnomAD rs771863444
- Missense
- Variant Prioritization Score for Impact Estimate 0.237
- REVEL 0.18
- MetaLR 0.11
- MetaSVM -1.02
- CADD 19.30
- PolyPhen-2 0.99
- SIFT 0.33
- Most common in the South Asian population (allele frequency 3.5e-05)
- Structural context available