Q59R (p.Gln59Arg) variant of LPA (Apolipoprotein(a))
Q59R (p.Gln59Arg) in LPA (Apolipoprotein(a)) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data and structural context.
Q59R (p.Gln59Arg) variant details
- p.Gln59Arg
- ExAC rs766900075
- TOPMed rs766900075
- gnomAD rs766900075
- Missense
- Variant Prioritization Score for Impact Estimate 0.0827
- REVEL 0.05
- MetaLR 0.03
- MetaSVM -1.05
- CADD 0.00
- PolyPhen-2 0.33
- SIFT 0.72
- Most common in the Finnish in Finland (FIN) population (allele frequency 1.9e-05)
- Structural context available