Q34K (p.Gln34Lys) variant of LPA (Apolipoprotein(a))
Q34K (p.Gln34Lys) in LPA (Apolipoprotein(a)) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
Q34K (p.Gln34Lys) variant details
- p.Gln34Lys
- ESP rs370228332
- ExAC rs370228332
- TOPMed rs370228332
- gnomAD rs370228332
- Missense
- Variant Prioritization Score for Impact Estimate 0.168
- REVEL 0.08
- MetaLR 0.03
- MetaSVM -0.99
- CADD 0.81
- PolyPhen-2 0.35
- SIFT 0.94
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available