Q26R (p.Gln26Arg) variant of LPA (Apolipoprotein(a))
Q26R (p.Gln26Arg) in LPA (Apolipoprotein(a)) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
Q26R (p.Gln26Arg) variant details
- p.Gln26Arg
- gnomAD rs1265428461
- Missense
- Variant Prioritization Score for Impact Estimate 0.309
- REVEL 0.20
- MetaLR 0.10
- MetaSVM -0.93
- CADD 22.00
- PolyPhen-2 0.97
- SIFT 0.65
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available