P68R (p.Pro68Arg) variant of LPA (Apolipoprotein(a))
P68R (p.Pro68Arg) in LPA (Apolipoprotein(a)) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data and structural context.
P68R (p.Pro68Arg) variant details
- p.Pro68Arg
- gnomAD rs1255140519
- Missense
- Variant Prioritization Score for Impact Estimate 0.466
- REVEL 0.33
- MetaLR 0.28
- MetaSVM -0.75
- CADD 22.90
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available