P19S (p.Pro19Ser) variant of LPA (Apolipoprotein(a))
P19S (p.Pro19Ser) in LPA (Apolipoprotein(a)) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
P19S (p.Pro19Ser) variant details
- p.Pro19Ser
- gnomAD rs1779985045
- Missense
- Variant Prioritization Score for Impact Estimate 0.142
- REVEL 0.04
- MetaLR 0.09
- MetaSVM -1.01
- CADD 0.81
- PolyPhen-2 0.14
- SIFT 0.57
- Most common in the Latino/Admixed American population (allele frequency 6.6e-05)
- Structural context available