P19R (p.Pro19Arg) variant of LPA (Apolipoprotein(a))
P19R (p.Pro19Arg) in LPA (Apolipoprotein(a)) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
P19R (p.Pro19Arg) variant details
- p.Pro19Arg
- gnomAD rs1188266967
- Missense
- Variant Prioritization Score for Impact Estimate 0.32
- REVEL 0.13
- AlphaMissense 0.19
- MetaLR 0.11
- MetaSVM -1.02
- CADD 21.90
- PolyPhen-2 0.62
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available