P120L (p.Pro120Leu) variant of LPA (Apolipoprotein(a))
P120L (p.Pro120Leu) in LPA (Apolipoprotein(a)) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
P120L (p.Pro120Leu) variant details
- p.Pro120Leu
- gnomAD rs200212358
- Missense
- Variant Prioritization Score for Impact Estimate 0.119
- REVEL 0.05
- MetaLR 0.04
- MetaSVM -1.02
- CADD 7.24
- PolyPhen-2 0.38
- SIFT 0.20
- Most common in the Non-Finnish European population (allele frequency 6.3e-05)
- Structural context available