N61D (p.Asn61Asp) variant of LPA (Apolipoprotein(a))
N61D (p.Asn61Asp) in LPA (Apolipoprotein(a)) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
N61D (p.Asn61Asp) variant details
- p.Asn61Asp
- TOPMed rs1396282902
- gnomAD rs1396282902
- Missense
- Variant Prioritization Score for Impact Estimate 0.14
- REVEL 0.17
- MetaLR 0.04
- MetaSVM -1.04
- CADD 0.00
- PolyPhen-2 0.36
- SIFT 0.11
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available