M55V (p.Met55Val) variant of LPA (Apolipoprotein(a))
M55V (p.Met55Val) in LPA (Apolipoprotein(a)) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
M55V (p.Met55Val) variant details
- p.Met55Val
- 1000Genomes rs375385826
- ESP rs375385826
- ExAC rs375385826
- TOPMed rs375385826
- Missense
- Variant Prioritization Score for Impact Estimate 0.269
- REVEL 0.19
- MetaLR 0.15
- MetaSVM -0.97
- CADD 15.20
- PolyPhen-2 0.68
- SIFT 0.18
- Most common in the 1KG:BEB population (allele frequency 0.0051)
- Structural context available