K4E (p.Lys4Glu) variant of LPA (Apolipoprotein(a))
K4E (p.Lys4Glu) in LPA (Apolipoprotein(a)) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
K4E (p.Lys4Glu) variant details
- p.Lys4Glu
- gnomAD rs1282846608
- Missense
- Variant Prioritization Score for Impact Estimate 0.179
- REVEL 0.07
- MetaLR 0.26
- MetaSVM -0.80
- CADD 13.60
- PolyPhen-2 0.35
- SIFT 0.89
- Most common in the Finnish in Finland (FIN) population (allele frequency 1.9e-05)
- Structural context available