H23Q (p.His23Gln) variant of LPA (Apolipoprotein(a))
H23Q (p.His23Gln) in LPA (Apolipoprotein(a)) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
H23Q (p.His23Gln) variant details
- p.His23Gln
- TOPMed rs1317484043
- gnomAD rs1317484043
- Missense
- Variant Prioritization Score for Impact Estimate 0.117
- REVEL 0.08
- MetaLR 0.09
- MetaSVM -0.95
- CADD 5.93
- SIFT 0.68
- Most common in the Non-Finnish European population (allele frequency 2.9e-05)
- Structural context available