G38D (p.Gly38Asp) variant of LPA (Apolipoprotein(a))
G38D (p.Gly38Asp) in LPA (Apolipoprotein(a)) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.66 / 1. The record also includes population frequency data and structural context.
G38D (p.Gly38Asp) variant details
- p.Gly38Asp
- TOPMed rs1444990255
- gnomAD rs1444990255
- Missense
- Variant Prioritization Score for Impact Estimate 0.659
- REVEL 0.57
- MetaLR 0.91
- MetaSVM 0.45
- CADD 23.30
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Middle Eastern population (allele frequency 0.00017)
- Structural context available