G208V (p.Gly208Val) variant of LPA (Apolipoprotein(a))
G208V (p.Gly208Val) in LPA (Apolipoprotein(a)) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data and structural context.
G208V (p.Gly208Val) variant details
- p.Gly208Val
- Ensembl rs1779835901
- Missense
- Variant Prioritization Score for Impact Estimate 0.125
- REVEL 0.08
- MetaLR 0.13
- MetaSVM -0.99
- CADD 8.17
- PolyPhen-2 0.74
- SIFT 0.05
- Most common in the East Asian population (allele frequency 0.00012)
- Structural context available