G208S (p.Gly208Ser) variant of LPA (Apolipoprotein(a))
G208S (p.Gly208Ser) in LPA (Apolipoprotein(a)) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
G208S (p.Gly208Ser) variant details
- p.Gly208Ser
- Ensembl rs1779835971
- Missense
- Variant Prioritization Score for Impact Estimate 0.135
- REVEL 0.11
- MetaLR 0.02
- MetaSVM -1.05
- CADD 8.33
- PolyPhen-2 0.04
- SIFT 1.00
- Most common in the HGDP:PALESTINIAN population (allele frequency 0.021)
- Structural context available