G185D (p.Gly185Asp) variant of LPA (Apolipoprotein(a))
G185D (p.Gly185Asp) in LPA (Apolipoprotein(a)) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
G185D (p.Gly185Asp) variant details
- p.Gly185Asp
- Ensembl rs1779837591
- Missense
- Variant Prioritization Score for Impact Estimate 0.198
- REVEL 0.19
- MetaLR 0.16
- MetaSVM -0.99
- CADD 12.60
- PolyPhen-2 1.00
- SIFT 0.95
- Most common in the African/African-American population (allele frequency 0.00013)
- Structural context available