F13Y (p.Phe13Tyr) variant of LPA (Apolipoprotein(a))
F13Y (p.Phe13Tyr) in LPA (Apolipoprotein(a)) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
F13Y (p.Phe13Tyr) variant details
- p.Phe13Tyr
- 1000Genomes rs559005335
- ExAC rs559005335
- gnomAD rs559005335
- Missense
- Variant Prioritization Score for Impact Estimate 0.301
- REVEL 0.12
- MetaLR 0.23
- MetaSVM -0.81
- CADD 18.20
- PolyPhen-2 0.03
- SIFT 1.00
- Most common in the South Asian population (allele frequency 3.5e-05)
- Structural context available