D92Y (p.Asp92Tyr) variant of LPA (Apolipoprotein(a))
D92Y (p.Asp92Tyr) in LPA (Apolipoprotein(a)) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data and structural context.
D92Y (p.Asp92Tyr) variant details
- p.Asp92Tyr
- gnomAD rs1339497082
- Missense
- Variant Prioritization Score for Impact Estimate 0.491
- REVEL 0.35
- MetaLR 0.43
- MetaSVM -0.61
- CADD 25.10
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 0.00028)
- Structural context available